2012年12月20日
The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells
The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells
Oleksandra Karpiuk1, Zeynab Najafova1, 4, Frank Kramer2, Magali Hennion1, Christina Galonska1, Annekatrin König5, Nicolas Snaidero6, Tanja Vogel7, Andrei Shchebet1, Yvonne Begus-Nahrmann1, Moustapha Kassem8, 9, Mikael Simons3, 6, Halyna Shcherbata5, Tim Beissbarth2 and Steven A. Johnsen1, 4
H2Bub increases during differentiation of mesenchymal stem cells.
H2Bub is regulated by CDK9-WAC-RNF40.
H2Bub plays a central role in bivalent state of lineage-specific genes and stem cell differentiation
（担当：松村）