2009年3月10日

エピゲノム勉強会

・Nature 2月19日号:yeast のCryptic Unstable Transcript (CUT) と bidirectional promoter の関係についての論文 ２本
Bidirectional promoters generate pervasive transcription in yeast
Zhenyu Xu1*, Wu Wei1*, Julien Gagneur1, Fabiana Perocchi1, Sandra Clauder-Mu¨nster1, Jurgi Camblong2, Elisa Guffanti3, Franc，oise Stutz3, Wolfgang Huber4 & Lars M. teinmetz1

(Letters)
Widespread bidirectional promoters are the major source of cryptic transcripts in yeast
Helen Neil1, Christophe Malabat1, Yves d'Aubenton-Carafa2, Zhenyu Xu3, Lars M. Steinmetz3 & Alain Jacquier1

Nature GENE
Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization
Yair Field1,5, Yvonne Fondufe-Mittendorf2,5, Irene K Moore2, Piotr Mieczkowski3, Noam Kaplan1,Yaniv Lubling1, Jason D Lieb3, Jonathan Widom2 & Eran Segal1,4

 
・ユビキチンを介したシグナル伝達について
Molecular Cell 33, 275-286
Nonproteolytic Functions of Ubiquitin in Cell Signaling
 

・JBCのcellular inhibitor for SUV39H1論文
Inhibition of SUV39H1 methyltransferase activity by DBC1
Zhenyu Li, Lihong Chen, Neha Kabra, Chuangui Wang1, Jia Fang, and Jiandong Chen*
Molecular Oncology Department, H. Lee Moffitt Cancer Center and Research Institute, 12902
Magnolia Drive, Tampa, FL 33612, U.S.A. 1Institute of Biomedical Sciences, East China Normal University, Shanghai, China

 
・HIF1結合部位の統合的解析とヒストンメチル化維持のための転写活性化機構
Integrative analysis of HIF binding and transactivation reveals its role in main taining histone methylation homeostasis.
Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL.
Proc Natl Acad Sci U S A. 2009 Mar 2. [Epub ahead of print]